Biological mode of action of Clostridium difficile toxin A: a novel enterotoxin
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چکیده
منابع مشابه
Clostridium difficile enterotoxin (toxin A): new results.
JOHN STEPHEN,* SUSAN C. REDMOND,* TIMOTHY J. MITCHELL,* JULIAN KETLEY,* DAVID C. A. CANDY,? DOUGLAS W. BURDONt and RICHARD DANIEL§ *Department of Microbiology. University of Birmingham, P.O. Box 363, Birmingham B15 ZTT, U.K., tlnstitute of Child Health, Francis Road, Edgbaston, Birmingham B16 8ET. U.K. , $Department of Microbiology, General Hospital, Steelhouse Lane, Birmingham B4 6NH U.K. , an...
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severe, interstitial pneumonitis of undetermined cause. The remaining animals were anaesthetised, systemically perfused with buffered solutions of paraformaldehyde followed by glutaraldehyde, and tissue prepared for examination in 1 m epoxy cross-sections stained with toluidine-blue. Examination of cortex, cerebellum, spinal cord, sciatic-nerve complex, and gastrocnemius muscle revealed no toxi...
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Hemorrhagic toxin (toxin HT) was purified from Clostridium sordellii culture filtrate. The purification steps included ultrafiltration through an XM-100 membrane filter and immunoaffinity chromatography, using a monoclonal antibody to toxin A of Clostridium difficile as the ligand. Toxin HT migrated as a major band with a molecular weight of 525,000 and a minor band at 450,000 on nondenaturing ...
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15 صفحه اولEFFECT OF AMYGDALUS COMMUNIS ON GROWTH AND TOXIN PRODUCTION OF CLOSTRIDIUM DIFFICILE
It is known that the major etiologic agent of pseudomembranous colitis in man is Clostridium difficile. With respect to traditional use of almond paste in the treatment of infantile diarrhea, we studied the effects of the aqueous extract of Amygdalus communis (AEAC) on the growth and toxin production of Clostridium difficile in culture medium and the rabbit ligated ileal loop. Three groups...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1987
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-23-3-211